MolNFT v1 · #478164 · protein
AlphaFold monomer V2.0 prediction for transient receptor potential cation channel subfamily M member 4 (Q9ESQ5)
Q9ESQ5: “AlphaFold monomer V2.0 prediction for transient receptor potential cation channel subfamily M member 4…”. 17 pockets (best druggability 0.76). MolNFT v1 #478164 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9ESQ5
- Type
- protein
- Length
- 1,208 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xdF2b063d4B94F3f46D117B1af99A846bD4a59284
- Molecule
- Transient receptor potential cation channel subfamily M member 4
- UniProt
- Q9ESQ5
- Pockets
- 17 · best druggability 0.76
Structure
1 distinct chain · 58% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transient receptor potential cation channel subfamily M member 4 | protein | 1208 | 58% helix, 8% strand | Q9ESQ5 |
Pockets
17 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 129 | 0.76 | 0.95 | 34 | empty |
| 2 | 782 | 0.76 | 0.80 | 65 | empty |
| 3 | 370 | 0.68 | 0.81 | 53 | empty |
| 4 | 321 | 0.61 | 0.78 | 31 | empty |
| 5 | 192 | 0.55 | 0.79 | 31 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9ESQ5
- Elsewhere: UniProt Q9ESQ5 · AlphaFold DB Q9ESQ5
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