MolNFT v1 · #475927 · protein
AlphaFold monomer V2.0 prediction for tryptophan synthase alpha chain (P0A877)
P0A877: “AlphaFold monomer V2.0 prediction for tryptophan synthase alpha chain (P0A877)”. 3 pockets (best druggability 0.67). MolNFT v1 #475927 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P0A877
- Type
- protein
- Length
- 268 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd1A2963012bEcbC7A8f505464439Ab678C48936f
- Molecule
- Tryptophan synthase alpha chain
- UniProt
- P0A877
- Pockets
- 3 · best druggability 0.67
Structure
1 distinct chain · 50% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tryptophan synthase alpha chain | protein | 268 | 50% helix, 15% strand | P0A877 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 178 | 0.67 | 0.86 | 46 | empty |
| 2 | 71 | 0.37 | 0.77 | 13 | empty |
| 3 | 65 | 0.30 | 0.74 | 18 | empty |
Compared structures
- 1WQ5 · Crystal structure of tryptophan synthase alpha-subunit from Escherichia coli · an experimental structure of the same protein · chain A against B, TM-score 0.89
- 1WQ5 · Crystal structure of tryptophan synthase alpha-subunit from escherichia COLI · an experimental structure of the same protein · chain A against B, TM-score 0.89
- 1V7Y · Crystal structure of tryptophan synthase alpha-subunit from Escherichia coli at room… · an experimental structure of the same protein · chain A against B, TM-score 0.89
- 1V7Y · Crystal structure of tryptophan synthase alpha-subunit from escherichia COLI at room… · an experimental structure of the same protein · chain A against B, TM-score 0.89
- 1XC4 · Crystal structure of wild-type tryptophan synthase alpha-subunits from escherichia COLI · an experimental structure of the same protein · chain A against A, TM-score 0.87
- 1XC4 · Crystal structure of wild-type tryptophan synthase alpha-subunits from Escherichia coli · an experimental structure of the same protein · chain A against A, TM-score 0.87
- 1XCF · Crystal structure of P28L/Y173F tryptophan synthase alpha-subunits from Escherichia coli · an experimental structure of the same protein · chain A against A, TM-score 0.84
- 1XCF · Crystal structure of P28L/Y173F tryptophan synthase alpha-subunits from escherichia COLI · an experimental structure of the same protein · chain A against A, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A877
- Elsewhere: UniProt P0A877 · AlphaFold DB P0A877
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