MolNFT v1 · #475728 · protein
AlphaFold monomer V2.0 prediction for transient receptor potential cation channel subfamily a member 1 homolog (Q18297)
Q18297: “AlphaFold monomer V2.0 prediction for transient receptor potential cation channel subfamily a member 1…”. 8 pockets (best druggability 0.71). MolNFT v1 #475728 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q18297
- Type
- protein
- Length
- 1,211 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x976760e64f70E9f04f69B77B1d3c519B728e5a66
- Molecule
- Transient receptor potential cation channel subfamily a member 1 homolog
- UniProt
- Q18297
- Pockets
- 8 · best druggability 0.71
Structure
1 distinct chain · 59% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transient receptor potential cation channel subfamily a member 1 homolog | protein | 1211 | 59% helix, 3% strand | Q18297 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 751 | 0.71 | 0.78 | 59 | empty |
| 2 | 608 | 0.68 | 0.77 | 43 | empty |
| 3 | 121 | 0.61 | 0.86 | 27 | empty |
| 4 | 187 | 0.49 | 0.76 | 26 | empty |
| 5 | 119 | 0.47 | 0.79 | 18 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q18297
- Elsewhere: UniProt Q18297 · AlphaFold DB Q18297
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