MolNFT v1 · #475297 · protein
AlphaFold monomer V2.0 prediction for methylenetetrahydrofolate-- tRNA-(uracil-5-)-methyltransferase trmfo (Q46K52)
Q46K52: “AlphaFold monomer V2.0 prediction for methylenetetrahydrofolate-- tRNA-(uracil-5-)-methyltransferase trmfo…”. 6 pockets (best druggability 0.75). MolNFT v1 #475297 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q46K52
- Type
- protein
- Length
- 467 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xe79229995410d23f4cc5cf100E458Ad3DD58ed38
- Molecule
- Methylenetetrahydrofolate-- tRNA-(uracil-5-)-methyltransferase trmfo
- UniProt
- Q46K52
- Pockets
- 6 · best druggability 0.75
Structure
1 distinct chain · 39% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methylenetetrahydrofolate-- tRNA-(uracil-5-)-methyltransferase trmfo | protein | 467 | 39% helix, 17% strand | Q46K52 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 653 | 0.75 | 0.81 | 80 | empty |
| 2 | 173 | 0.59 | 0.82 | 20 | empty |
| 3 | 306 | 0.56 | 0.76 | 36 | empty |
| 4 | 99 | 0.45 | 0.79 | 15 | empty |
| 5 | 70 | 0.31 | 0.74 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q46K52
- Elsewhere: UniProt Q46K52 · AlphaFold DB Q46K52
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