MolNFT v1 · #473572 · protein
AlphaFold monomer V2.0 prediction for tRNA (GUANOSINE(18)-2'-O)-methyltransferase (Q07527)
Q07527: “AlphaFold monomer V2.0 prediction for tRNA (GUANOSINE(18)-2'-O)-methyltransferase (Q07527)”. 13 pockets (best druggability 0.66). MolNFT v1 #473572 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q07527
- Type
- protein
- Length
- 1,436 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6210d44A4915BD5e50Be1f4196Df3F7d8ebD63e8
- Molecule
- TRNA (GUANOSINE(18)-2'-O)-methyltransferase
- UniProt
- Q07527
- Pockets
- 13 · best druggability 0.66
Structure
1 distinct chain · 64% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | TRNA (GUANOSINE(18)-2'-O)-methyltransferase | protein | 1436 | 64% helix, 3% strand | Q07527 |
Pockets
13 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 625 | 0.66 | 0.75 | 46 | empty |
| 2 | 338 | 0.61 | 0.78 | 41 | empty |
| 3 | 144 | 0.61 | 0.84 | 21 | empty |
| 4 | 150 | 0.55 | 0.81 | 21 | empty |
| 5 | 162 | 0.50 | 0.78 | 26 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q07527
- Elsewhere: UniProt Q07527 · AlphaFold DB Q07527
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