MolNFT v1 · #473388 · protein
AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIP12 (B4F6W9)
B4F6W9: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIP12 (B4F6W9)”. 20 pockets (best druggability 0.76). MolNFT v1 #473388 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B4F6W9
- Type
- protein
- Length
- 2,056 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0EA189b2343A464f560b44103f6A3396Da1dA8a9
- Molecule
- E3 ubiquitin-protein ligase TRIP12
- UniProt
- B4F6W9
- Pockets
- 20 · best druggability 0.76
Structure
1 distinct chain · 38% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase TRIP12 | protein | 2056 | 38% helix, 6% strand | B4F6W9 |
Pockets
20 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 372 | 0.76 | 0.86 | 48 | empty |
| 2 | 509 | 0.75 | 0.83 | 51 | empty |
| 3 | 533 | 0.75 | 0.82 | 56 | empty |
| 4 | 463 | 0.70 | 0.81 | 48 | empty |
| 5 | 352 | 0.68 | 0.81 | 36 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B4F6W9
- Elsewhere: UniProt B4F6W9 · AlphaFold DB B4F6W9
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