MolNFT v1 · #473198 · protein
AlphaFold monomer V2.0 prediction for tripartite motif-containing protein 42 (Q8IWZ5)
Q8IWZ5: “AlphaFold monomer V2.0 prediction for tripartite motif-containing protein 42 (Q8IWZ5)”. 5 pockets (best druggability 0.61). MolNFT v1 #473198 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8IWZ5
- Type
- protein
- Length
- 723 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x27e67Efe562B17F05415cb640674a08713e14067
- Molecule
- Tripartite motif-containing protein 42
- UniProt
- Q8IWZ5
- Pockets
- 5 · best druggability 0.61
Structure
1 distinct chain · 27% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tripartite motif-containing protein 42 | protein | 723 | 27% helix, 15% strand | Q8IWZ5 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 492 | 0.61 | 0.74 | 42 | empty |
| 2 | 293 | 0.52 | 0.74 | 30 | empty |
| 3 | 54 | 0.35 | 0.78 | 12 | empty |
| 4 | 57 | 0.33 | 0.77 | 14 | empty |
| 5 | 58 | 0.33 | 0.77 | 15 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IWZ5
- Elsewhere: UniProt Q8IWZ5 · AlphaFold DB Q8IWZ5
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