MolNFT v1 · #473170 · protein
AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIM32 (Q8CH72)
Q8CH72: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIM32 (Q8CH72)”. 8 pockets (best druggability 0.74). MolNFT v1 #473170 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8CH72
- Type
- protein
- Length
- 655 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x463Be372c11f96eeBDBC4baa0AB3805D50aD7Ccd
- Molecule
- E3 ubiquitin-protein ligase TRIM32
- UniProt
- Q8CH72
- Pockets
- 8 · best druggability 0.74
Structure
1 distinct chain · 26% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase TRIM32 | protein | 655 | 26% helix, 28% strand | Q8CH72 |
Pockets
8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 993 | 0.74 | 0.77 | 90 | empty |
| 2 | 234 | 0.50 | 0.75 | 31 | empty |
| 3 | 129 | 0.47 | 0.78 | 24 | empty |
| 4 | 71 | 0.42 | 0.80 | 17 | empty |
| 5 | 52 | 0.41 | 0.82 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8CH72
- Elsewhere: UniProt Q8CH72 · AlphaFold DB Q8CH72
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