MolNFT v1 · #473140 · protein
AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase midline-1 (O70583)
O70583: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase midline-1 (O70583)”. 3 pockets (best druggability 0.49). MolNFT v1 #473140 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O70583
- Type
- protein
- Length
- 680 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9e5E98E011361C5888c92e2CDb7652E02Bd5C7Ed
- Molecule
- E3 ubiquitin-protein ligase midline-1
- UniProt
- O70583
- Pockets
- 3 · best druggability 0.49
Structure
1 distinct chain · 31% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase midline-1 | protein | 680 | 31% helix, 25% strand | O70583 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 68 | 0.49 | 0.85 | 22 | empty |
| 2 | 164 | 0.42 | 0.74 | 32 | empty |
| 3 | 79 | 0.34 | 0.75 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O70583
- Elsewhere: UniProt O70583 · AlphaFold DB O70583
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.