MolNFT v1 · #472706 · protein
AlphaFold monomer V2.0 prediction for thyrotropin-releasing hormone- degrading ectoenzyme (Q10836)
Q10836 · Thyrotropin-releasing hormone-degrading ectoenzyme: “AlphaFold monomer V2.0 prediction for thyrotropin-releasing hormone- degrading ectoenzyme (Q10836)”. 8 pockets (best druggability 0.83). MolNFT v1 #472706 on GenesisL1: 3D…
- Accession
- Q10836
- Type
- protein
- Length
- 1,025 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0c9a548C6Ddf03912482aE0Ef0a8883d6fbEC3A9
- Molecule
- Thyrotropin-releasing hormone-degrading ectoenzyme
- UniProt
- Q10836
- Pockets
- 8 · best druggability 0.83
Structure
1 distinct chain · 45% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thyrotropin-releasing hormone-degrading ectoenzyme | protein | 1025 | 45% helix, 19% strand | Q10836 |
Pockets
8 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 693 | 0.83 | 0.87 | 77 | empty |
| 2 | 435 | 0.82 | 0.89 | 59 | empty |
| 3 | 334 | 0.66 | 0.81 | 36 | empty |
| 4 | 249 | 0.58 | 0.79 | 33 | empty |
| 5 | 55 | 0.53 | 0.88 | 17 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q10836
- Elsewhere: UniProt Q10836 · AlphaFold DB Q10836
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