MolNFT v1 · #472705 · protein
AlphaFold monomer V2.0 prediction for thyrotropin-releasing hormone- degrading ectoenzyme (Q8K093)
Q8K093 · Thyrotropin-releasing hormone-degrading ectoenzyme: “AlphaFold monomer V2.0 prediction for thyrotropin-releasing hormone- degrading ectoenzyme (Q8K093)”. 11 pockets (best druggability 0.85). MolNFT v1 #472705 on GenesisL1: 3D…
- Accession
- Q8K093
- Type
- protein
- Length
- 1,025 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x53c93E7A401667370377170c205e199E26177691
- Molecule
- Thyrotropin-releasing hormone-degrading ectoenzyme
- UniProt
- Q8K093
- Pockets
- 11 · best druggability 0.85
Structure
1 distinct chain · 45% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thyrotropin-releasing hormone-degrading ectoenzyme | protein | 1025 | 45% helix, 20% strand | Q8K093 |
Pockets
11 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 834 | 0.85 | 0.87 | 110 | empty |
| 2 | 276 | 0.79 | 0.91 | 36 | empty |
| 3 | 355 | 0.66 | 0.80 | 33 | empty |
| 4 | 164 | 0.59 | 0.82 | 29 | empty |
| 5 | 127 | 0.58 | 0.84 | 23 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8K093
- Elsewhere: UniProt Q8K093 · AlphaFold DB Q8K093
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