MolNFT v1 · #472220 · protein

AlphaFold monomer V2.0 prediction for TNF receptor-associated factor 6 (Q6IWL4)

Q6IWL4: “AlphaFold monomer V2.0 prediction for TNF receptor-associated factor 6 (Q6IWL4)”. 3 pockets (best druggability 0.74). MolNFT v1 #472220 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q6IWL4
Type: protein
Length: 542 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xC1C81C5d9568Be2795E0Bd2e795B6bD277CaDb67
Molecule: TNF receptor-associated factor 6
UniProt: Q6IWL4
Pockets: 3 · best druggability 0.74

Structure

1 distinct chain · 30% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	TNF receptor-associated factor 6	protein	542	30% helix, 20% strand	Q6IWL4

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1028	0.74	0.77	83	empty
2	282	0.59	0.78	30	empty
3	108	0.52	0.82	24	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

6MYD · Structure of zebrafish TRAF6 in complex with sting ctt · an experimental structure of the same protein · chain A against A, TM-score 0.27
6MYD · Structure of zebrafish TRAF6 in complex with STING CTT · an experimental structure of the same protein · chain A against A, TM-score 0.27

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6IWL4
Elsewhere: UniProt Q6IWL4 · AlphaFold DB Q6IWL4

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