MolNFT v1 · #472042 · protein

AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member 11B (O08712)

O08712: “AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member 11B (O08712)”. 3 pockets (best druggability 0.43). MolNFT v1 #472042 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O08712
Type: protein
Length: 401 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9B130d619fCFc21d0D08E5Ce38Cf42A5fbe230CB
Molecule: Tumor necrosis factor receptor superfamily member 11B
UniProt: O08712
Pockets: 3 · best druggability 0.43

Structure

1 distinct chain · 37% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tumor necrosis factor receptor superfamily member 11B	protein	401	37% helix, 18% strand	O08712

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	127	0.43	0.76	22	empty
2	59	0.28	0.74	12	empty
3	54	0.28	0.74	11	empty

Modifications

Observed in the structure: 11 disulfide (disulfide).

Compared structures

4E4D · Crystal structure of mouse RANKL-OPG complex · an experimental structure of the same protein · chain A against R, TM-score 0.33
4E4D · Crystal structure of mouse rankl-opg complex · an experimental structure of the same protein · chain A against R, TM-score 0.33

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O08712
Elsewhere: UniProt O08712 · AlphaFold DB O08712

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