MolNFT v1 · #471911 · protein
AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (Q6XPS3)
Q6XPS3: “AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (Q6XPS3)”. 6 pockets (best druggability 0.74). MolNFT v1 #471911 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6XPS3
- Type
- protein
- Length
- 522 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x62eFb6d03b91c54ae5eD1b71762fBF04bB754e08
- Molecule
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2
- UniProt
- Q6XPS3
- Pockets
- 6 · best druggability 0.74
Structure
1 distinct chain · 44% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 | protein | 522 | 44% helix, 18% strand | Q6XPS3 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 418 | 0.74 | 0.84 | 44 | empty |
| 2 | 675 | 0.67 | 0.76 | 61 | empty |
| 3 | 118 | 0.47 | 0.79 | 26 | empty |
| 4 | 110 | 0.47 | 0.79 | 17 | empty |
| 5 | 123 | 0.43 | 0.77 | 18 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6XPS3
- Elsewhere: UniProt Q6XPS3 · AlphaFold DB Q6XPS3
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