MolNFT v1 · #471282 · protein
AlphaFold monomer V2.0 prediction for triosephosphate isomerase, glycosomal (P52270)
P52270: “AlphaFold monomer V2.0 prediction for triosephosphate isomerase, glycosomal (P52270)”. 3 pockets (best druggability 0.41). MolNFT v1 #471282 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P52270
- Type
- protein
- Length
- 251 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBF0D2e107Ce1EcD2C4369B042274201DB719AaAF
- Molecule
- Triosephosphate isomerase, glycosomal
- UniProt
- P52270
- Pockets
- 3 · best druggability 0.41
Structure
1 distinct chain · 47% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Triosephosphate isomerase, glycosomal | protein | 251 | 47% helix, 16% strand | P52270 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 93 | 0.41 | 0.78 | 15 | empty |
| 2 | 74 | 0.38 | 0.78 | 14 | empty |
| 3 | 66 | 0.34 | 0.76 | 22 | empty |
Compared structures
- 1SUX · CRYSTALLOGRAPHIC ANALYSIS OF THE COMPLEX BETWEEN TRIOSEPHOSPHATE ISOMERASE FROM… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1SUX · Crystallographic analysis of the complex between triosephosphate isomerase from… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 2OMA · Crystallographic analysis of a chemically modified triosephosphate isomerase from… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 2OMA · Crystallographic analysis of a chemically modified triosephosphate isomerase from… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1TCD · Trypanosoma cruzi triosephosphate isomerase · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1TCD · Trypanosoma cruzi triosephosphate isomerase · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1CI1 · Crystal structure of triosephosphate isomerase from trypanosoma cruzi in hexane · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1CI1 · Crystal structure of triosephosphate isomerase from trypanosoma cruzi in hexane · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 4HHP · Crystal structure of triosephosphate isomerase from trypanosoma cruzi, mutant e105d · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 4HHP · Crystal structure of triosephosphate isomerase from trypanosoma cruzi, mutant E105D · an experimental structure of the same protein · chain A against B, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P52270
- Elsewhere: UniProt P52270 · AlphaFold DB P52270
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