MolNFT v1 · #470317 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase TOS3 (P43637)
P43637: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase TOS3 (P43637)”. 6 pockets (best druggability 0.79). MolNFT v1 #470317 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P43637
- Type
- protein
- Length
- 560 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
- Molecule
- SERINE/THREONINE-protein kinase TOS3
- UniProt
- P43637
- Pockets
- 6 · best druggability 0.79
Structure
1 distinct chain · 24% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase TOS3 | protein | 560 | 24% helix, 12% strand | P43637 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1031 | 0.79 | 0.81 | 95 | empty |
| 2 | 279 | 0.68 | 0.83 | 35 | empty |
| 3 | 228 | 0.64 | 0.82 | 36 | empty |
| 4 | 140 | 0.46 | 0.77 | 14 | empty |
| 5 | 69 | 0.39 | 0.79 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43637
- Elsewhere: UniProt P43637 · AlphaFold DB P43637
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