MolNFT v1 · #470117 · protein
AlphaFold monomer V2.0 prediction for type 2 DNA topoisomerase 6 subunit B (Q58434)
Q58434: “AlphaFold monomer V2.0 prediction for type 2 DNA topoisomerase 6 subunit B (Q58434)”. 7 pockets (best druggability 0.78). MolNFT v1 #470117 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q58434
- Type
- protein
- Length
- 660 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBeB220F0B5b0C48F46B5DDd3E3b071BC0827f8D6
- Molecule
- Type 2 DNA topoisomerase 6 subunit B
- UniProt
- Q58434
- Pockets
- 7 · best druggability 0.78
Structure
1 distinct chain · 50% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Type 2 DNA topoisomerase 6 subunit B | protein | 660 | 50% helix, 18% strand | Q58434 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 496 | 0.78 | 0.85 | 55 | empty |
| 2 | 314 | 0.57 | 0.76 | 38 | empty |
| 3 | 100 | 0.57 | 0.86 | 14 | empty |
| 4 | 266 | 0.51 | 0.75 | 41 | empty |
| 5 | 119 | 0.41 | 0.76 | 28 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q58434
- Elsewhere: UniProt Q58434 · AlphaFold DB Q58434
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