MolNFT v1 · #470094 · protein

AlphaFold monomer V2.0 prediction for type 2 DNA topoisomerase 6 subunit a (Q8TQF8)

Q8TQF8: “AlphaFold monomer V2.0 prediction for type 2 DNA topoisomerase 6 subunit a (Q8TQF8)”. 5 pockets (best druggability 0.54). MolNFT v1 #470094 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8TQF8
Type: protein
Length: 373 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x0e1cf82d2E07cf9FCd6ce0e123Bc9584e4F92CaD
Molecule: Type 2 DNA topoisomerase 6 subunit a
UniProt: Q8TQF8
Pockets: 5 · best druggability 0.54

Structure

1 distinct chain · 53% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Type 2 DNA topoisomerase 6 subunit a	protein	373	53% helix, 19% strand	Q8TQF8

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	271	0.54	0.76	29	empty
2	51	0.42	0.83	13	empty
3	85	0.40	0.78	14	empty
4	51	0.31	0.77	11	empty
5	52	0.28	0.75	14	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8TQF8
Elsewhere: UniProt Q8TQF8 · AlphaFold DB Q8TQF8

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