MolNFT v1 · #470068 · protein
AlphaFold monomer V2.0 prediction for DNA topoisomerase 3 (O60126)
O60126: “AlphaFold monomer V2.0 prediction for DNA topoisomerase 3 (O60126)”. 4 pockets (best druggability 0.71). MolNFT v1 #470068 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O60126
- Type
- protein
- Length
- 622 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9B130d619fCFc21d0D08E5Ce38Cf42A5fbe230CB
- Molecule
- DNA topoisomerase 3
- UniProt
- O60126
- Pockets
- 4 · best druggability 0.71
Structure
1 distinct chain · 43% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA topoisomerase 3 | protein | 622 | 43% helix, 20% strand | O60126 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 804 | 0.71 | 0.77 | 84 | empty |
| 2 | 152 | 0.43 | 0.75 | 27 | empty |
| 3 | 165 | 0.42 | 0.74 | 22 | empty |
| 4 | 50 | 0.29 | 0.75 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60126
- Elsewhere: UniProt O60126 · AlphaFold DB O60126
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