MolNFT v1 · #470061 · protein
AlphaFold monomer V2.0 prediction for DNA topoisomerase 3 (A0A0L0P6P7)
A0A0L0P6P7: “AlphaFold monomer V2.0 prediction for DNA topoisomerase 3 (A0A0L0P6P7)”. 4 pockets (best druggability 0.65). MolNFT v1 #470061 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A0A0L0P6P7
- Type
- protein
- Length
- 640 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4b9B28863F57e8B425c826d0587315Ae2D052587
- Molecule
- DNA topoisomerase 3
- Pockets
- 4 · best druggability 0.65
Structure
1 distinct chain · 44% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA topoisomerase 3 | protein | 640 | 44% helix, 20% strand | — |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 468 | 0.65 | 0.78 | 65 | empty |
| 2 | 438 | 0.59 | 0.75 | 48 | empty |
| 3 | 56 | 0.41 | 0.82 | 15 | empty |
| 4 | 66 | 0.32 | 0.76 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
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