MolNFT v1 · #470020 · protein
AlphaFold monomer V2.0 prediction for putative DNA topoisomerase 2, mitochondrial (P34534)
P34534: “AlphaFold monomer V2.0 prediction for putative DNA topoisomerase 2, mitochondrial (P34534)”. 10 pockets (best druggability 0.81). MolNFT v1 #470020 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P34534
- Type
- protein
- Length
- 1,170 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x025f3b1a898b05AD2731bE6Ab72687b5920c4A3F
- Molecule
- Putative DNA topoisomerase 2, mitochondrial
- UniProt
- P34534
- Pockets
- 10 · best druggability 0.81
Structure
1 distinct chain · 40% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative DNA topoisomerase 2, mitochondrial | protein | 1170 | 40% helix, 19% strand | P34534 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 972 | 0.81 | 0.83 | 105 | empty |
| 2 | 203 | 0.73 | 0.89 | 34 | empty |
| 3 | 333 | 0.67 | 0.81 | 35 | empty |
| 4 | 152 | 0.52 | 0.79 | 25 | empty |
| 5 | 155 | 0.45 | 0.75 | 21 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P34534
- Elsewhere: UniProt P34534 · AlphaFold DB P34534
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