MolNFT v1 · #470014 · protein
AlphaFold monomer V2.0 prediction for DNA topoisomerase 2-beta (Q64399)
Q64399: “AlphaFold monomer V2.0 prediction for DNA topoisomerase 2-beta (Q64399)”. 14 pockets (best druggability 0.81). MolNFT v1 #470014 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q64399
- Type
- protein
- Length
- 1,612 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x71112d4fF7ebb3b617963c05f052289e073082FD
- Molecule
- DNA topoisomerase 2-beta
- UniProt
- Q64399
- Pockets
- 14 · best druggability 0.81
Structure
1 distinct chain · 32% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA topoisomerase 2-beta | protein | 1612 | 32% helix, 14% strand | Q64399 |
Pockets
14 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1008 | 0.81 | 0.82 | 79 | empty |
| 2 | 275 | 0.73 | 0.87 | 36 | empty |
| 3 | 355 | 0.70 | 0.82 | 48 | empty |
| 4 | 442 | 0.66 | 0.78 | 44 | empty |
| 5 | 238 | 0.65 | 0.83 | 35 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q64399
- Elsewhere: UniProt Q64399 · AlphaFold DB Q64399
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