MolNFT v1 · #469974 · protein
AlphaFold monomer V2.0 prediction for DNA topoisomerase 1 (Q9ZDK2)
Q9ZDK2: “AlphaFold monomer V2.0 prediction for DNA topoisomerase 1 (Q9ZDK2)”. 10 pockets (best druggability 0.72). MolNFT v1 #469974 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9ZDK2
- Type
- protein
- Length
- 776 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x55a29e902aF350A0fC464c94d3358163a842f994
- Molecule
- DNA topoisomerase 1
- UniProt
- Q9ZDK2
- Pockets
- 10 · best druggability 0.72
Structure
1 distinct chain · 39% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA topoisomerase 1 | protein | 776 | 39% helix, 23% strand | Q9ZDK2 |
Pockets
10 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 827 | 0.72 | 0.78 | 92 | empty |
| 2 | 460 | 0.57 | 0.73 | 59 | empty |
| 3 | 195 | 0.44 | 0.73 | 39 | empty |
| 4 | 59 | 0.38 | 0.79 | 20 | empty |
| 5 | 56 | 0.33 | 0.78 | 12 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9ZDK2
- Elsewhere: UniProt Q9ZDK2 · AlphaFold DB Q9ZDK2
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