MolNFT v1 · #469432 · protein
AlphaFold monomer V2.0 prediction for topoisomerase 1-associated factor 1 (Q6CUU2)
Q6CUU2: “AlphaFold monomer V2.0 prediction for topoisomerase 1-associated factor 1 (Q6CUU2)”. 10 pockets (best druggability 0.72). MolNFT v1 #469432 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6CUU2
- Type
- protein
- Length
- 1,162 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4d07E6a23DeB6B95bd9b90EcB67368b7e8D3B77e
- Molecule
- Topoisomerase 1-associated factor 1
- UniProt
- Q6CUU2
- Pockets
- 10 · best druggability 0.72
Structure
1 distinct chain · 57% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Topoisomerase 1-associated factor 1 | protein | 1162 | 57% helix, 3% strand | Q6CUU2 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 389 | 0.72 | 0.83 | 46 | empty |
| 2 | 607 | 0.70 | 0.78 | 69 | empty |
| 3 | 769 | 0.68 | 0.75 | 65 | empty |
| 4 | 244 | 0.62 | 0.81 | 26 | empty |
| 5 | 314 | 0.54 | 0.75 | 35 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6CUU2
- Elsewhere: UniProt Q6CUU2 · AlphaFold DB Q6CUU2
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