MolNFT v1 · #469420 · protein
AlphaFold monomer V2.0 prediction for topoisomerase 1-associated factor 1 (Q4W9M7)
Q4W9M7: “AlphaFold monomer V2.0 prediction for topoisomerase 1-associated factor 1 (Q4W9M7)”. 11 pockets (best druggability 0.74). MolNFT v1 #469420 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q4W9M7
- Type
- protein
- Length
- 1,176 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x627DfEbfC08CCF86E151D6C3143e17Eada033427
- Molecule
- Topoisomerase 1-associated factor 1
- UniProt
- Q4W9M7
- Pockets
- 11 · best druggability 0.74
Structure
1 distinct chain · 53% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Topoisomerase 1-associated factor 1 | protein | 1176 | 53% helix, 2% strand | Q4W9M7 |
Pockets
11 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 941 | 0.74 | 0.78 | 78 | empty |
| 2 | 366 | 0.63 | 0.78 | 38 | empty |
| 3 | 293 | 0.60 | 0.78 | 41 | empty |
| 4 | 140 | 0.46 | 0.77 | 24 | empty |
| 5 | 143 | 0.43 | 0.76 | 18 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4W9M7
- Elsewhere: UniProt Q4W9M7 · AlphaFold DB Q4W9M7
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