MolNFT v1 · #469364 · protein
AlphaFold monomer V2.0 prediction for type 2 DNA topoisomerase 6 subunit B-like (Q5Q0E6)
Q5Q0E6: “AlphaFold monomer V2.0 prediction for type 2 DNA topoisomerase 6 subunit B-like (Q5Q0E6)”. 5 pockets (best druggability 0.71). MolNFT v1 #469364 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q5Q0E6
- Type
- protein
- Length
- 473 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB44F19a0cb161828322eEEd13F55d4C3C34938d2
- Molecule
- Type 2 DNA topoisomerase 6 subunit B-like
- UniProt
- Q5Q0E6
- Pockets
- 5 · best druggability 0.71
Structure
1 distinct chain · 32% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Type 2 DNA topoisomerase 6 subunit B-like | protein | 473 | 32% helix, 26% strand | Q5Q0E6 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 892 | 0.71 | 0.76 | 79 | empty |
| 2 | 80 | 0.44 | 0.81 | 20 | empty |
| 3 | 53 | 0.34 | 0.78 | 15 | empty |
| 4 | 54 | 0.32 | 0.77 | 14 | empty |
| 5 | 76 | 0.32 | 0.74 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5Q0E6
- Elsewhere: UniProt Q5Q0E6 · AlphaFold DB Q5Q0E6
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