MolNFT v1 · #469104 · protein
AlphaFold monomer V2.0 prediction for poly [ADP-ribose] polymerase tankyrase-2 (Q3UES3)
Q3UES3: “AlphaFold monomer V2.0 prediction for poly [ADP-ribose] polymerase tankyrase-2 (Q3UES3)”. 11 pockets (best druggability 0.73). MolNFT v1 #469104 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q3UES3
- Type
- protein
- Length
- 1,166 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf72109dFe971f199ADf76784570501d113E7b6A6
- Molecule
- Poly [ADP-ribose] polymerase tankyrase-2
- UniProt
- Q3UES3
- Pockets
- 11 · best druggability 0.73
Structure
1 distinct chain · 43% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Poly [ADP-ribose] polymerase tankyrase-2 | protein | 1166 | 43% helix, 5% strand | Q3UES3 |
Pockets
11 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 645 | 0.73 | 0.80 | 57 | empty |
| 2 | 305 | 0.60 | 0.78 | 31 | empty |
| 3 | 279 | 0.57 | 0.77 | 28 | empty |
| 4 | 152 | 0.44 | 0.75 | 30 | empty |
| 5 | 80 | 0.43 | 0.80 | 22 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3UES3
- Elsewhere: UniProt Q3UES3 · AlphaFold DB Q3UES3
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