MolNFT v1 · #468853 · protein
AlphaFold monomer V2.0 prediction for transmembrane protease serine 6 (Q8IU80)
Q8IU80: “AlphaFold monomer V2.0 prediction for transmembrane protease serine 6 (Q8IU80)”. 7 pockets (best druggability 0.77). MolNFT v1 #468853 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8IU80
- Type
- protein
- Length
- 811 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
- Molecule
- Transmembrane protease serine 6
- UniProt
- Q8IU80
- Pockets
- 7 · best druggability 0.77
Structure
1 distinct chain · 15% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transmembrane protease serine 6 | protein | 811 | 15% helix, 32% strand | Q8IU80 |
Pockets
7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 948 | 0.77 | 0.80 | 102 | empty |
| 2 | 162 | 0.57 | 0.81 | 22 | empty |
| 3 | 271 | 0.57 | 0.78 | 31 | empty |
| 4 | 256 | 0.52 | 0.75 | 26 | empty |
| 5 | 113 | 0.51 | 0.81 | 22 | empty |
Modifications
Observed in the structure: 18 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IU80
- Elsewhere: UniProt Q8IU80 · AlphaFold DB Q8IU80
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