MolNFT v1 · #467210 · protein
AlphaFold monomer V2.0 prediction for transketolase 1 (P57927)
P57927: “AlphaFold monomer V2.0 prediction for transketolase 1 (P57927)”. 7 pockets (best druggability 0.56). MolNFT v1 #467210 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P57927
- Type
- protein
- Length
- 668 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x35CE9E273dC599B97173f7Fa74880CacB153321E
- Molecule
- Transketolase 1
- UniProt
- P57927
- Pockets
- 7 · best druggability 0.56
Structure
1 distinct chain · 46% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transketolase 1 | protein | 668 | 46% helix, 14% strand | P57927 |
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 251 | 0.56 | 0.78 | 39 | empty |
| 2 | 73 | 0.49 | 0.84 | 18 | empty |
| 3 | 88 | 0.40 | 0.77 | 15 | empty |
| 4 | 79 | 0.36 | 0.76 | 22 | empty |
| 5 | 50 | 0.30 | 0.77 | 12 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P57927
- Elsewhere: UniProt P57927 · AlphaFold DB P57927
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