MolNFT v1 · #465291 · protein

AlphaFold monomer V2.0 prediction for thyroglobulin (F1RRV3)

F1RRV3: “AlphaFold monomer V2.0 prediction for thyroglobulin (F1RRV3)”. 20 pockets (best druggability 0.88). MolNFT v1 #465291 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: F1RRV3
Type: protein
Length: 2,692 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xF8cD1d8d93E9783063700De244A6e3cf6A195579
Molecule: Thyroglobulin
UniProt: F1RRV3
Pockets: 20 · best druggability 0.88

Structure

1 distinct chain · 28% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Thyroglobulin	protein	2692	28% helix, 21% strand	F1RRV3

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1164	0.88	0.89	116	empty
2	790	0.80	0.83	88	empty
3	355	0.78	0.87	28	empty
4	844	0.78	0.81	100	empty
5	414	0.75	0.85	50	empty

Modifications

Observed in the structure: 58 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt F1RRV3
Elsewhere: UniProt F1RRV3 · AlphaFold DB F1RRV3

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