MolNFT v1 · #465195 · protein
AlphaFold monomer V2.0 prediction for thermosome subunit alpha (P48424)
P48424: “AlphaFold monomer V2.0 prediction for thermosome subunit alpha (P48424)”. 2 pockets (best druggability 0.76). MolNFT v1 #465195 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P48424
- Type
- protein
- Length
- 545 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4F3500FD13628563884A773578190b4E4dCd3a28
- Molecule
- Thermosome subunit alpha
- UniProt
- P48424
- Pockets
- 2 · best druggability 0.76
Structure
1 distinct chain · 48% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thermosome subunit alpha | protein | 545 | 48% helix, 18% strand | P48424 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 343 | 0.76 | 0.87 | 42 | empty |
| 2 | 52 | 0.27 | 0.75 | 15 | empty |
Compared structures
- 1A6E · Thermosome-mg-ADP-ALF3 complex · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 1A6E · Thermosome-mg-ADP-ALF3 complex · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 1A6D · Thermosome from T. acidophilum · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 1A6D · Thermosome from T. acidophilum · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 1ASS · Apical domain of the chaperonin from thermoplasma acidophilum · an experimental structure of the same protein · chain A against A, TM-score 0.26
- 1ASS · Apical domain of the chaperonin from thermoplasma acidophilum · an experimental structure of the same protein · chain A against A, TM-score 0.26
- 1ASX · Apical domain of the chaperonin from thermoplasma acidophilum · an experimental structure of the same protein · chain A against A, TM-score 0.26
- 1ASX · Apical domain of the chaperonin from thermoplasma acidophilum · an experimental structure of the same protein · chain A against A, TM-score 0.26
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P48424
- Elsewhere: UniProt P48424 · AlphaFold DB P48424
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