MolNFT v1 · #465130 · protein

AlphaFold monomer V2.0 prediction for prothrombin (Q5R537)

Q5R537: “AlphaFold monomer V2.0 prediction for prothrombin (Q5R537)”. 7 pockets (best druggability 0.74). MolNFT v1 #465130 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q5R537
Type: protein
Length: 623 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xCcE0f7d4E847A12eE8F3c53aeE79dC9c9B1cB849
Molecule: Prothrombin
UniProt: Q5R537
Pockets: 7 · best druggability 0.74

Structure

1 distinct chain · 21% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Prothrombin	protein	623	21% helix, 18% strand	Q5R537

Pockets

7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	424	0.74	0.84	49	empty
2	522	0.68	0.78	69	empty
3	149	0.55	0.81	22	empty
4	145	0.55	0.82	24	empty
5	193	0.53	0.79	25	empty

Modifications

Observed in the structure: 12 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5R537
Elsewhere: UniProt Q5R537 · AlphaFold DB Q5R537

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.