MolNFT v1 · #462975 · protein
AlphaFold monomer V2.0 prediction for phosphomethylpyrimidine synthase (Q9A6Q5)
Q9A6Q5: “AlphaFold monomer V2.0 prediction for phosphomethylpyrimidine synthase (Q9A6Q5)”. 8 pockets (best druggability 0.72). MolNFT v1 #462975 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9A6Q5
- Type
- protein
- Length
- 612 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xa73BAb1DabE4333A884D03393eAa10c3B4215494
- Molecule
- Phosphomethylpyrimidine synthase
- UniProt
- Q9A6Q5
- Pockets
- 8 · best druggability 0.72
Structure
1 distinct chain · 44% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphomethylpyrimidine synthase | protein | 612 | 44% helix, 10% strand | Q9A6Q5 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 215 | 0.72 | 0.88 | 37 | empty |
| 2 | 317 | 0.72 | 0.85 | 40 | empty |
| 3 | 126 | 0.55 | 0.82 | 19 | empty |
| 4 | 126 | 0.48 | 0.79 | 28 | empty |
| 5 | 178 | 0.43 | 0.73 | 29 | empty |
Compared structures
- 4S2A · Crystal structure of Caulobacter crescentus ThiC with Fe4S4 cluster at remote site (holo… · an experimental structure of the same protein · chain A against A, TM-score 0.89
- 4S2A · Crystal structure of caulobacter crescentus thic with FE4S4 cluster at remote site (holo… · an experimental structure of the same protein · chain A against A, TM-score 0.89
- 3EPO · Crystal structure of Caulobacter crescentus ThiC complexed with HMP-P · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 3EPO · Crystal structure of caulobacter crescentus thic complexed with hmp-P · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 3EPN · Crystal structure of Caulobacter crescentus ThiC complexed with imidazole ribonucleotide · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 3EPN · Crystal structure of caulobacter crescentus thic complexed with imidazole ribonucleotide · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 3EPM · Crystal structure of Caulobacter crescentus ThiC · an experimental structure of the same protein · chain A against A, TM-score 0.84
- 3EPM · Crystal structure of caulobacter crescentus thic · an experimental structure of the same protein · chain A against A, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9A6Q5
- Elsewhere: UniProt Q9A6Q5 · AlphaFold DB Q9A6Q5
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