MolNFT v1 · #462637 · protein
AlphaFold monomer V2.0 prediction for thyroxine-binding globulin (P50450)
P50450: “AlphaFold monomer V2.0 prediction for thyroxine-binding globulin (P50450)”. 6 pockets (best druggability 0.62). MolNFT v1 #462637 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P50450
- Type
- protein
- Length
- 412 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x79a905d858Ce72991FD6E7a9C6498620f42E146D
- Molecule
- Thyroxine-binding globulin
- UniProt
- P50450
- Pockets
- 6 · best druggability 0.62
Structure
1 distinct chain · 29% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thyroxine-binding globulin | protein | 412 | 29% helix, 30% strand | P50450 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 151 | 0.62 | 0.84 | 18 | empty |
| 2 | 122 | 0.48 | 0.79 | 17 | empty |
| 3 | 133 | 0.44 | 0.76 | 20 | empty |
| 4 | 135 | 0.43 | 0.76 | 21 | empty |
| 5 | 83 | 0.41 | 0.79 | 21 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P50450
- Elsewhere: UniProt P50450 · AlphaFold DB P50450
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