MolNFT v1 · #462621 · protein
AlphaFold monomer V2.0 prediction for thyroid hormone receptor alpha (O57606)
O57606: “AlphaFold monomer V2.0 prediction for thyroid hormone receptor alpha (O57606)”. 6 pockets (best druggability 0.83). MolNFT v1 #462621 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O57606
- Type
- protein
- Length
- 408 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0EA189b2343A464f560b44103f6A3396Da1dA8a9
- Molecule
- Thyroid hormone receptor alpha
- UniProt
- O57606
- Pockets
- 6 · best druggability 0.83
Structure
1 distinct chain · 56% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thyroid hormone receptor alpha | protein | 408 | 56% helix, 5% strand | O57606 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 179 | 0.83 | 0.98 | 32 | empty |
| 2 | 135 | 0.46 | 0.78 | 16 | empty |
| 3 | 123 | 0.45 | 0.77 | 20 | empty |
| 4 | 59 | 0.34 | 0.77 | 14 | empty |
| 5 | 50 | 0.33 | 0.78 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O57606
- Elsewhere: UniProt O57606 · AlphaFold DB O57606
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