MolNFT v1 · #461953 · protein
AlphaFold monomer V2.0 prediction for TGF-beta receptor type-1 (Q64729)
Q64729: “AlphaFold monomer V2.0 prediction for TGF-beta receptor type-1 (Q64729)”. 3 pockets (best druggability 0.73). MolNFT v1 #461953 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q64729
- Type
- protein
- Length
- 503 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1141c59a573b52725A219545C456190739feD131
- Molecule
- TGF-beta receptor type-1
- UniProt
- Q64729
- Pockets
- 3 · best druggability 0.73
Structure
1 distinct chain · 35% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | TGF-beta receptor type-1 | protein | 503 | 35% helix, 19% strand | Q64729 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 55 | 0.73 | 0.99 | 17 | empty |
| 2 | 384 | 0.69 | 0.81 | 45 | empty |
| 3 | 96 | 0.33 | 0.73 | 19 | empty |
Modifications
Observed in the structure: 5 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q64729
- Elsewhere: UniProt Q64729 · AlphaFold DB Q64729
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