MolNFT v1 · #461941 · protein
AlphaFold monomer V2.0 prediction for transforming growth factor beta-3 proprotein (P16047)
P16047: “AlphaFold monomer V2.0 prediction for transforming growth factor beta-3 proprotein (P16047)”. 7 pockets (best druggability 0.74). MolNFT v1 #461941 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P16047
- Type
- protein
- Length
- 412 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7012c0b45c68a2c067644b9d3e5DDa06892c6957
- Molecule
- Transforming growth factor beta-3 proprotein
- UniProt
- P16047
- Pockets
- 7 · best druggability 0.74
Structure
1 distinct chain · 27% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transforming growth factor beta-3 proprotein | protein | 412 | 27% helix, 27% strand | P16047 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 889 | 0.74 | 0.78 | 67 | empty |
| 2 | 103 | 0.50 | 0.82 | 19 | empty |
| 3 | 105 | 0.41 | 0.76 | 16 | empty |
| 4 | 106 | 0.34 | 0.73 | 16 | empty |
| 5 | 84 | 0.33 | 0.74 | 16 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16047
- Elsewhere: UniProt P16047 · AlphaFold DB P16047
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