MolNFT v1 · #461934 · protein
AlphaFold monomer V2.0 prediction for transforming growth factor beta-2 proprotein (P61811)
P61811: “AlphaFold monomer V2.0 prediction for transforming growth factor beta-2 proprotein (P61811)”. 4 pockets (best druggability 0.73). MolNFT v1 #461934 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P61811
- Type
- protein
- Length
- 414 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x01Ad51C82dd521245552f447f4fb0a71abB50C3B
- Molecule
- Transforming growth factor beta-2 proprotein
- UniProt
- P61811
- Pockets
- 4 · best druggability 0.73
Structure
1 distinct chain · 27% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transforming growth factor beta-2 proprotein | protein | 414 | 27% helix, 28% strand | P61811 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 904 | 0.73 | 0.77 | 82 | empty |
| 2 | 556 | 0.63 | 0.75 | 47 | empty |
| 3 | 113 | 0.44 | 0.77 | 19 | empty |
| 4 | 72 | 0.31 | 0.74 | 15 | empty |
Modifications
Observed in the structure: 5 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P61811
- Elsewhere: UniProt P61811 · AlphaFold DB P61811
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