MolNFT v1 · #461930 · protein
AlphaFold monomer V2.0 prediction for transforming growth factor beta-1 proprotein (P50414)
P50414: “AlphaFold monomer V2.0 prediction for transforming growth factor beta-1 proprotein (P50414)”. 6 pockets (best druggability 0.48). MolNFT v1 #461930 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P50414
- Type
- protein
- Length
- 390 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x05A042b1250f9bed02e55EeF26666C383876906A
- Molecule
- Transforming growth factor beta-1 proprotein
- UniProt
- P50414
- Pockets
- 6 · best druggability 0.48
Structure
1 distinct chain · 25% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transforming growth factor beta-1 proprotein | protein | 390 | 25% helix, 28% strand | P50414 |
Pockets
6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 227 | 0.48 | 0.74 | 31 | empty |
| 2 | 131 | 0.40 | 0.74 | 24 | empty |
| 3 | 79 | 0.37 | 0.77 | 17 | empty |
| 4 | 92 | 0.36 | 0.75 | 17 | empty |
| 5 | 70 | 0.34 | 0.76 | 16 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P50414
- Elsewhere: UniProt P50414 · AlphaFold DB P50414
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