MolNFT v1 · #461923 · protein
AlphaFold monomer V2.0 prediction for transforming growth factor beta-1 proprotein (O19011)
O19011: “AlphaFold monomer V2.0 prediction for transforming growth factor beta-1 proprotein (O19011)”. 5 pockets (best druggability 0.65). MolNFT v1 #461923 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O19011
- Type
- protein
- Length
- 390 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4d07E6a23DeB6B95bd9b90EcB67368b7e8D3B77e
- Molecule
- Transforming growth factor beta-1 proprotein
- UniProt
- O19011
- Pockets
- 5 · best druggability 0.65
Structure
1 distinct chain · 23% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transforming growth factor beta-1 proprotein | protein | 390 | 23% helix, 29% strand | O19011 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 496 | 0.65 | 0.77 | 46 | empty |
| 2 | 85 | 0.37 | 0.76 | 15 | empty |
| 3 | 73 | 0.35 | 0.76 | 16 | empty |
| 4 | 78 | 0.34 | 0.75 | 16 | empty |
| 5 | 68 | 0.31 | 0.75 | 17 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O19011
- Elsewhere: UniProt O19011 · AlphaFold DB O19011
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