GL1X · GenesisL1 explorer

MolNFT v1 · #461777 · protein

AlphaFold monomer V2.0 prediction for septin and tuftelin-interacting protein 1 homolog (Q17784)

Q17784: “AlphaFold monomer V2.0 prediction for septin and tuftelin-interacting protein 1 homolog (Q17784)”. 4 pockets (best druggability 0.57). MolNFT v1 #461777 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q17784
Type
protein
Length
830 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xa73BAb1DabE4333A884D03393eAa10c3B4215494
Molecule
Septin and tuftelin-interacting protein 1 homolog
UniProt
Q17784
Pockets
4 · best druggability 0.57

Structure

1 distinct chain · 49% helix, 5% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASeptin and tuftelin-interacting protein 1 homologprotein83049% helix, 5% strandQ17784

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12520.570.7829empty
21040.460.7922empty
31200.440.7727empty
4680.310.7416empty

Compared structures

  • 8RO1 · Structure of the C. elegans Intron Lariat Spliceosome double-primed for disassembly… · an experimental structure of the same protein · chain A against TF, TM-score 0.41
  • 8RO0 · Structure of the C. elegans Intron Lariat Spliceosome primed for disassembly (ILS') · an experimental structure of the same protein · chain A against TF, TM-score 0.40

Analyse

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