GL1X · GenesisL1 explorer

MolNFT v1 · #461615 · protein

AlphaFold monomer V2.0 prediction for RNA polymerase II transcription factor B subunit 3 (Q03290)

Q03290: “AlphaFold monomer V2.0 prediction for RNA polymerase II transcription factor B subunit 3 (Q03290)”. 2 pockets (best druggability 0.36). MolNFT v1 #461615 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q03290
Type
protein
Length
321 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xEa58c7534E5701aA8370E0fAEb19b7e14653e69c
Molecule
RNA polymerase II transcription factor B subunit 3
UniProt
Q03290
Pockets
2 · best druggability 0.36

Structure

1 distinct chain · 60% helix, 4% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARNA polymerase II transcription factor B subunit 3protein32160% helix, 4% strandQ03290

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1760.360.7614empty
2640.360.7813empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

  • 7O4L · Yeast TFIIH in the expanded state within the pre-initiation complex · an experimental structure of the same protein · chain A against 3, TM-score 0.39
  • 7O4L · Yeast tfiih in the expanded state within the pre-initiation complex · an experimental structure of the same protein · chain A against 3, TM-score 0.39
  • 7O4I · Yeast RNA polymerase II transcription pre-initiation complex with initial transcription… · an experimental structure of the same protein · chain A against 3, TM-score 0.39
  • 7O4J · Yeast RNA polymerase II transcription pre-initiation complex (consensus) · an experimental structure of the same protein · chain A against 3, TM-score 0.39
  • 7O4J · Yeast RNA polymerase II transcription pre-initiation complex (consensus) · an experimental structure of the same protein · chain A against 3, TM-score 0.39
  • 7O72 · Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA · an experimental structure of the same protein · chain A against 3, TM-score 0.39
  • 7O72 · Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA · an experimental structure of the same protein · chain A against 3, TM-score 0.39
  • 7O75 · Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA · an experimental structure of the same protein · chain A against 3, TM-score 0.39
  • 7O75 · Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA · an experimental structure of the same protein · chain A against 3, TM-score 0.39
  • 7O73 · Yeast RNA polymerase II transcription pre-initiation complex with closed distorted… · an experimental structure of the same protein · chain A against 3, TM-score 0.39
  • 7O4K · Yeast tfiih in the contracted state within the pre-initiation complex · an experimental structure of the same protein · chain A against 3, TM-score 0.39
  • 6GYM · Structure of a yeast closed complex with distorted DNA (ccdist) · an experimental structure of the same protein · chain A against 3, TM-score 0.38

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