MolNFT v1 · #461615 · protein
AlphaFold monomer V2.0 prediction for RNA polymerase II transcription factor B subunit 3 (Q03290)
Q03290: “AlphaFold monomer V2.0 prediction for RNA polymerase II transcription factor B subunit 3 (Q03290)”. 2 pockets (best druggability 0.36). MolNFT v1 #461615 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q03290
- Type
- protein
- Length
- 321 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xEa58c7534E5701aA8370E0fAEb19b7e14653e69c
- Molecule
- RNA polymerase II transcription factor B subunit 3
- UniProt
- Q03290
- Pockets
- 2 · best druggability 0.36
Structure
1 distinct chain · 60% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA polymerase II transcription factor B subunit 3 | protein | 321 | 60% helix, 4% strand | Q03290 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 76 | 0.36 | 0.76 | 14 | empty |
| 2 | 64 | 0.36 | 0.78 | 13 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7O4L · Yeast TFIIH in the expanded state within the pre-initiation complex · an experimental structure of the same protein · chain A against 3, TM-score 0.39
- 7O4L · Yeast tfiih in the expanded state within the pre-initiation complex · an experimental structure of the same protein · chain A against 3, TM-score 0.39
- 7O4I · Yeast RNA polymerase II transcription pre-initiation complex with initial transcription… · an experimental structure of the same protein · chain A against 3, TM-score 0.39
- 7O4J · Yeast RNA polymerase II transcription pre-initiation complex (consensus) · an experimental structure of the same protein · chain A against 3, TM-score 0.39
- 7O4J · Yeast RNA polymerase II transcription pre-initiation complex (consensus) · an experimental structure of the same protein · chain A against 3, TM-score 0.39
- 7O72 · Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA · an experimental structure of the same protein · chain A against 3, TM-score 0.39
- 7O72 · Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA · an experimental structure of the same protein · chain A against 3, TM-score 0.39
- 7O75 · Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA · an experimental structure of the same protein · chain A against 3, TM-score 0.39
- 7O75 · Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA · an experimental structure of the same protein · chain A against 3, TM-score 0.39
- 7O73 · Yeast RNA polymerase II transcription pre-initiation complex with closed distorted… · an experimental structure of the same protein · chain A against 3, TM-score 0.39
- 7O4K · Yeast tfiih in the contracted state within the pre-initiation complex · an experimental structure of the same protein · chain A against 3, TM-score 0.39
- 6GYM · Structure of a yeast closed complex with distorted DNA (ccdist) · an experimental structure of the same protein · chain A against 3, TM-score 0.38
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q03290
- Elsewhere: UniProt Q03290 · AlphaFold DB Q03290
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