MolNFT v1 · #461605 · protein
AlphaFold monomer V2.0 prediction for general transcription and DNA repair factor iih subunit TFB2 (Q6CLR2)
Q6CLR2: “AlphaFold monomer V2.0 prediction for general transcription and DNA repair factor iih subunit TFB2 (Q6CLR2)”. 5 pockets (best druggability 0.70). MolNFT v1 #461605 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6CLR2
- Type
- protein
- Length
- 496 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xC631cbCDF0F9A68578F6bb83aD28877742912F30
- Molecule
- General transcription and DNA repair factor iih subunit TFB2
- UniProt
- Q6CLR2
- Pockets
- 5 · best druggability 0.70
Structure
1 distinct chain · 51% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | General transcription and DNA repair factor iih subunit TFB2 | protein | 496 | 51% helix, 12% strand | Q6CLR2 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 500 | 0.70 | 0.80 | 52 | empty |
| 2 | 87 | 0.41 | 0.78 | 21 | empty |
| 3 | 56 | 0.35 | 0.79 | 15 | empty |
| 4 | 73 | 0.35 | 0.76 | 16 | empty |
| 5 | 54 | 0.30 | 0.75 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6CLR2
- Elsewhere: UniProt Q6CLR2 · AlphaFold DB Q6CLR2
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