MolNFT v1 · #461251 · protein

AlphaFold monomer V2.0 prediction for methylcytosine dioxygenase TET2 (Q4JK59)

Q4JK59: “AlphaFold monomer V2.0 prediction for methylcytosine dioxygenase TET2 (Q4JK59)”. 7 pockets (best druggability 0.69). MolNFT v1 #461251 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q4JK59
Type: protein
Length: 1,912 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xD7Ea924320b052B91736C1c86B3FD4b725512701
Molecule: Methylcytosine dioxygenase TET2
UniProt: Q4JK59
Pockets: 7 · best druggability 0.69

Structure

1 distinct chain · 9% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Methylcytosine dioxygenase TET2	protein	1912	9% helix, 6% strand	Q4JK59

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.69	0.97	17	empty
2	629	0.65	0.75	59	empty
3	102	0.55	0.84	28	empty
4	140	0.43	0.76	18	empty
5	86	0.42	0.79	22	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4JK59
Elsewhere: UniProt Q4JK59 · AlphaFold DB Q4JK59

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