MolNFT v1 · #461161 · protein
AlphaFold monomer V2.0 prediction for telomerase reverse transcriptase (O76332)
O76332: “AlphaFold monomer V2.0 prediction for telomerase reverse transcriptase (O76332)”. 16 pockets (best druggability 0.76). MolNFT v1 #461161 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O76332
- Type
- protein
- Length
- 1,132 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xAe60a245FF4c8aB8aEe81bfA8C2c2242098434D7
- Molecule
- Telomerase reverse transcriptase
- UniProt
- O76332
- Pockets
- 16 · best druggability 0.76
Structure
1 distinct chain · 48% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Telomerase reverse transcriptase | protein | 1132 | 48% helix, 13% strand | O76332 |
Pockets
16 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1115 | 0.76 | 0.78 | 86 | empty |
| 2 | 576 | 0.69 | 0.78 | 51 | empty |
| 3 | 198 | 0.64 | 0.83 | 23 | empty |
| 4 | 430 | 0.63 | 0.77 | 39 | empty |
| 5 | 242 | 0.58 | 0.79 | 30 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O76332
- Elsewhere: UniProt O76332 · AlphaFold DB O76332
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