MolNFT v1 · #461158 · protein
AlphaFold monomer V2.0 prediction for telomerase reverse transcriptase (O70372)
O70372: “AlphaFold monomer V2.0 prediction for telomerase reverse transcriptase (O70372)”. 13 pockets (best druggability 0.70). MolNFT v1 #461158 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O70372
- Type
- protein
- Length
- 1,122 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x79a905d858Ce72991FD6E7a9C6498620f42E146D
- Molecule
- Telomerase reverse transcriptase
- UniProt
- O70372
- Pockets
- 13 · best druggability 0.70
Structure
1 distinct chain · 43% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Telomerase reverse transcriptase | protein | 1122 | 43% helix, 13% strand | O70372 |
Pockets
13 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 920 | 0.70 | 0.75 | 76 | empty |
| 2 | 374 | 0.58 | 0.76 | 43 | empty |
| 3 | 237 | 0.56 | 0.78 | 27 | empty |
| 4 | 129 | 0.54 | 0.82 | 26 | empty |
| 5 | 198 | 0.50 | 0.76 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O70372
- Elsewhere: UniProt O70372 · AlphaFold DB O70372
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