MolNFT v1 · #460382 · protein
AlphaFold monomer V2.0 prediction for topoisomerase I damage affected protein 2 (P40045)
P40045: “AlphaFold monomer V2.0 prediction for topoisomerase I damage affected protein 2 (P40045)”. 2 pockets (best druggability 0.42). MolNFT v1 #460382 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P40045
- Type
- protein
- Length
- 126 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x595Ca4bb5814aa4883f946Db6B5e4d02B50e5E75
- Molecule
- Topoisomerase I damage affected protein 2
- UniProt
- P40045
- Pockets
- 2 · best druggability 0.42
Structure
1 distinct chain · 26% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Topoisomerase I damage affected protein 2 | protein | 126 | 26% helix, 25% strand | P40045 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 64 | 0.42 | 0.81 | 15 | empty |
| 2 | 72 | 0.38 | 0.78 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P40045
- Elsewhere: UniProt P40045 · AlphaFold DB P40045
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