MolNFT v1 · #459962 · protein
AlphaFold monomer V2.0 prediction for transcobalamin-2 (Q9XSC9)
Q9XSC9: “AlphaFold monomer V2.0 prediction for transcobalamin-2 (Q9XSC9)”. 3 pockets (best druggability 0.78). MolNFT v1 #459962 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9XSC9
- Type
- protein
- Length
- 432 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x866b846BF04951b9214b46ED5E3FC54E8e4ab00f
- Molecule
- Transcobalamin-2
- UniProt
- Q9XSC9
- Pockets
- 3 · best druggability 0.78
Structure
1 distinct chain · 46% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcobalamin-2 | protein | 432 | 46% helix, 13% strand | Q9XSC9 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 972 | 0.78 | 0.80 | 66 | empty |
| 2 | 101 | 0.36 | 0.75 | 24 | empty |
| 3 | 52 | 0.26 | 0.73 | 14 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 2BBC · Structure of Cobalamin-complexed Bovine Transcobalamin in trigonal crystal form · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 2BBC · Structure of cobalamin-complexed bovine transcobalamin in trigonal crystal form · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 2BB6 · Structure of cobalamin-complexed bovine transcobalamin in monoclinic crystal form · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 2BB6 · Structure of Cobalamin-complexed Bovine Transcobalamin in Monoclinic Crystal Form · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 2V3P · Crystallographic analysis of beta-axial ligand substitutions in cobalamin bound to… · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 2V3P · Crystallographic analysis of beta-axial ligand substitutions in cobalamin bound to… · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 2V3N · Crystallographic analysis of upper axial ligand substitutions in cobalamin bound to… · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 2V3N · Crystallographic analysis of upper axial ligand substitutions in cobalamin bound to… · an experimental structure of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9XSC9
- Elsewhere: UniProt Q9XSC9 · AlphaFold DB Q9XSC9
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