MolNFT v1 · #459460 · protein
AlphaFold monomer V2.0 prediction for F-box-LIKE/WD repeat-containing protein TBL1XR1 (Q8BHJ5)
Q8BHJ5: “AlphaFold monomer V2.0 prediction for F-box-LIKE/WD repeat-containing protein TBL1XR1 (Q8BHJ5)”. 4 pockets (best druggability 0.80). MolNFT v1 #459460 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8BHJ5
- Type
- protein
- Length
- 514 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xaa53776A41fB2e67da75A96E8a53746b6874aAB4
- Molecule
- F-box-LIKE/WD repeat-containing protein TBL1XR1
- UniProt
- Q8BHJ5
- Pockets
- 4 · best druggability 0.80
Structure
1 distinct chain · 17% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | F-box-LIKE/WD repeat-containing protein TBL1XR1 | protein | 514 | 17% helix, 38% strand | Q8BHJ5 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1017 | 0.80 | 0.81 | 64 | empty |
| 2 | 69 | 0.34 | 0.76 | 17 | empty |
| 3 | 54 | 0.26 | 0.73 | 13 | empty |
| 4 | 62 | 0.25 | 0.71 | 14 | empty |
Compared structures
- 5NAF · Co-crystal structure of an MECP2 peptide with TBLR1 WD40 domain · an experimental structure of the same protein · chain A against A, TM-score 0.68
- 5NAF · Co-crystal structure of an MeCP2 peptide with TBLR1 WD40 domain · an experimental structure of the same protein · chain A against A, TM-score 0.68
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8BHJ5
- Elsewhere: UniProt Q8BHJ5 · AlphaFold DB Q8BHJ5
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