MolNFT v1 · #459116 · protein

AlphaFold monomer V2.0 prediction for tubulin beta-4 chain (P30883)

P30883: “AlphaFold monomer V2.0 prediction for tubulin beta-4 chain (P30883)”. 7 pockets (best druggability 0.58). MolNFT v1 #459116 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P30883
Type: protein
Length: 445 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xf96C5834Ad687e9EbeF5b6A56c77eb1420b55e4A
Molecule: Tubulin beta-4 chain
UniProt: P30883
Pockets: 7 · best druggability 0.58

Structure

1 distinct chain · 50% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tubulin beta-4 chain	protein	445	50% helix, 18% strand	P30883

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	203	0.58	0.81	35	empty
2	229	0.55	0.78	28	empty
3	60	0.34	0.77	18	empty
4	67	0.33	0.76	17	empty
5	63	0.30	0.75	13	empty

Compared structures

9EOK · Minus end of the vertebrate gamma-tubulin ring complex-capped microtubule · an experimental structure of the same protein · chain A against Y, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P30883
Elsewhere: UniProt P30883 · AlphaFold DB P30883

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